Serology

A comprehensive and relevant range of viral infections and diseases can be detected and monitored through our Virology Laboratory and services. Serology and molecular techniques are the mainstay of tests utilised in this department. A hub and spoke approach offers relevant molecular testing in the periphery (close to the patient) and centralised testing for certain other e.g. HIV resistance testing. Syndromic testing through means of molecular techniques, offered centrally and in the periphery, provides cost effective detection of a wide range of bacterial and viral disease in a short turn-around time.

Key aspects

Detection of Antibodies and Antigens for Disease Diagnosis:
Serology focuses on identifying antibodies or antigens in blood and other body fluids. These tests play a crucial role in diagnosing infectious diseases, autoimmune conditions, and immune responses to vaccination.

Assessment of Immune Status and Exposure History:
Serological assays help determine whether a patient has been exposed to a particular pathogen, whether immunity has developed, and whether past infections have resolved or remain active. This is particularly important for diseases such as hepatitis, HIV, rubella, and syphilis.

Screening and Confirmatory Testing for Infectious Diseases:
A wide range of infectious diseases—including viral, bacterial, and parasitic infections—can be detected using serology. Screening tests identify potential infections, while confirmatory assays ensure diagnostic accuracy and guide appropriate treatment.

Monitoring of Chronic and Acute Infections:
Serology supports the monitoring of disease progression by measuring antibody levels or specific immune markers over time. This assists clinicians in tracking response to treatment and determining disease stage or reactivation.

Autoimmune and Allergy Testing:
Serological techniques are widely used to detect autoantibodies associated with autoimmune disorders (such as ANA for lupus or rheumatoid factor for rheumatoid arthritis) and to measure allergen-specific IgE levels for allergy diagnosis.

Integration with Molecular and Virology Services:
Within FlowPath’s diagnostic framework, serology works alongside molecular and virology testing to provide comprehensive infectious disease diagnostics. This integrated approach ensures rapid and accurate detection of pathogens and supports syndromic testing strategies for efficient patient management.